To receive the weekly EBS newsletter
      Home            News          Advertising       Events         About us      Archive Issues     In-House Test Centres   
04.06.2018 Screening APIs under strictest containment conditions

AZO, Osterburken, Germany, points out that low occupational exposure limits and complex toxicological evaluations pose special challenges for processors and manufacturers of highly active substances with regard to process safety. On top of this, there are new regulations, such as the modified EU GMP directives, which came into force in March 2015. Thanks to engineering design solutions, today's plants now generate so little dust in regular operations that it is possible to rule out any threat to the health of plant operating staff from harmful dust. However, the situation is far more critical when maintenance or cleaning work has to be carried out.
Inspection hatches have to be opened in order to inspect working parts in machinery and plants. In the case of maintenance activities, maintenance staff have to remove worn components and install new replacement parts. In the past, this was only possible within isolators when smaller plants and machines were concerned or, when larger machines were concerned, by wearing full body protection. Installation in an isolator is not possible in the case of cyclone screeners for reasons of handling and space, which is why AZO developed the type DA Vario Containment screener which will be among innovations to be exhibited by the company on Stand C50, Hall 6.0, at next week’s ACHEMA.
With this newly designed screener, AZO provides an entirely new solution to satisfy the above-mentioned requirements: based on the DA screener, tried and tested in actual practice for years, and on the widespread practice of using flexible containment systems in the pharmaceutical industry, it is now feasible to open the familiar inspection hatch and to inspect the screen in this way without any dust escaping.
AZO cyclone screener type DA Vario Containment  

« Back