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17.02.2020 Simplifying cryogenic chemistry

De Dietrich Process Systems GmbH, Mainz, Germany, and InnoSyn BV, Geleen, the Netherlands, have jointly developed the CryoFlowSkid which enables three-step syntheses for the continuous production of chemical intermediates or active pharmaceutical ingredients in kg quantities per hour. In particular, syntheses with highly exothermic reaction steps and proceeding through unstable intermediates can be carried out in the CryoFlowSkid, reportedly with significantly higher efficiency than with a batch process. Thus the technology for organometallic chemistry, for example, can often be considerably intensified. The compact, mobile system can be operated in a typical chemical pilot plant environment and it is fully automated.

The system is highly modular so that, for example, the reactors can be easily exchanged. InnoSyn contributed the chemical process know-how and the flow reactors. These core components developed by InnoSyn are manufactured from different metals in a 3D printing process. De Dietrich Process Systems, as the manufacturer of the entire system, is responsible for the engineering, production and worldwide sales and service of the complete CryoFlowSkid. For this joint cooperation the two companies have signed a collaboration contract.;


The CryoFlowSkid from De Dietrich Process Systems incorporates flow reactors from InnoSyn

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