amixon GmbH, Paderborn, Germany, reports that  a pharmaceutical company has recently integrated an amixon® vertical mixer-drier into its production line to homogenise active agents under highly sterile conditions.                  

Working volumes vary between 0.3 and 3m³. This means that ideal mixing quality can be achieved when the device is filled to a level anywhere between 10% and 100%. The mixing process proceeds without creating any inactive regions, since the patented SinConvex® mixing device drives the materials upwards at the periphery of the mixing chamber and then allows them to flow downwards in the centre. Because individual components have to be handled very gently, the velocity at the circumference is no more than about 1m/s. Ideal mixing quality is achieved within a mixing time of between three and six minutes. 

When it comes to the discharge of the mixing goods, the new ComDisc®-system provides a carry-out of up to 99.997% and more. At the conclusion of each mixing process an automatic washing-in-place operation takes place by means of amixon’s patented WaterDragon® system. Further details of this technology will be featured on the amixon booth (1-304) at POWTECH. www.amixon.com 

 

 

Sterile mixer-drier for active agents from amixon